Xanthohumol improved cognitive flexibility in young mice

Xanthohumol improved cognitive flexibility in young mice.

The protein palmitoylation cycle has been shown to be important for protein signaling and synaptic plasticity. Data from our lab showed a change in the palmitoylation status of certain proteins with age. A greater percentage of the NMDA receptor subunits GluN2A and GluN2B, along with Fyn and PSD95 proteins, were palmitoylated in the old mice. The higher level of protein palmitoylation was also ...

Fitness and action monitoring: evidence for improved cognitive flexibility in young adults.

To improve behavior, one must detect errors and initiate subsequent corrective adaptations. This action monitoring process has been widely studied, but little is known about how one may improve this aspect of cognition. To examine the relationship between cardiorespiratory fitness and action monitoring, we recorded the error-related negativity (ERN), an event-related brain potential believed to...

Cognitive flexibility in young children: General or task-specific capacity?

Cognitive flexibility is the ability to adapt to changing tasks or problems. To test whether cognitive flexibility is a coherent cognitive capacity in young children, we tested 3- to 5-year-olds' performance on two forms of task switching, rule-based (Three Dimension Changes Card Sorting, 3DCCS) and inductive (Flexible Induction of Meaning-Animates and Objects, FIM-Ob and FIM-An), as well as te...

Cognitive Flexibility

Cognitive Flexibility and Its Dimensions in Patients with Gastrointestinal Diseases

  Abstract Introduction: Gastrointestinal diseases are one of the most common and chronic non-communicable diseases that impose high stress and cost on society and the health system. Objective: The present study aimed at comparing cognitive flexibility and its dimensions between gastrointestinal patients and healthy subjects. Materials and Methods: This is a comparative analytical study. Th...